Creating innovative solutions. Milestone
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Overview

Milestone Development Services is a consulting company dedicated to connecting industry needs with innovative technologies and solutions. Formed in 1998, Milestone provides information and insights to assist clients in the pharmaceutical industry, and businesses providing products and services to the industry. The purpose is to help clients: keep current with trends; develop or sustain relationships; increase presence in the field; devise development strategies and tactical plans.

The current activities of the company include training, workshops, symposia, and consulting. Milestone features industry-based applications training and events dedicated to the benchmarking of analytical performance for accelerated drug development. Much of the company's consulting and training is focused on the design, development, and implementation of customized LC/MS-based applications for accelerated development. Diverse pharmaceutical industry experiences provide a unique opportunity to serve as an extended or virtual research staff. Milestone is also available to assist with data interpretation for rapid, confidential response to your immediate needs.

For providers of technology and services, Milestone assists with market analysis and product development. The information and data collected, combined with industry insights, provide a unique capability for the effective targeting of application segments, product positioning, and format to address them. Key aspects of this service focus on:

Publications by Mike Lee

Protein Analysis using Mass Spectrometry: Accelerating Protein Biotherapeutics from Lab to Patient
Published June 2017
This book brings together the most current advances in the mass spectrometry technology and related method in protein analysis. It covers both qualitative and quantitative aspects of Mass Spectrometry protein analysis in drug discovery. Principles, Instrumentation, Technologies topics include MS of peptides, proteins, and ADCs , instrumentation in protein analysis, nanospray technology in MS protein analysis, and automation in MS protein analysis.

Oral Bioavailability Assessment: Basics and Strategies for Drug Discovery and Development
Published May 2017
Specifically geared to personnel in the pharmaceutical and biotechnology industries, this book describes the basics and challenges of oral bioavailability – one of the most significant hurdles in drug discovery and development.

Dried Blood Spots
Published May 2014
Dried Blood Spots features contributions from an international team of leading scientists in the field. Their contributions present a unique resource on the history, principles, procedures, methodologies, applications, and emerging technologies related to DBS.

Mass Spectrometry Handbook
Published April 2012
This unique reference provides an extensive library of methods used in mass spectrometry, covering applications of mass spectrometry in fields as diverse as drug discovery, environmental science, forensic science, clinical analysis, homeland security and more.

Mass Spectrometry in Drug Metabolism and Disposition:
Basic Principles and Applications

Published March 2011
This book examines the background, industrial context, process, analytical methodology, and technology of metabolite identification. It emphasizes the applications of metabolite identification in drug research. While primarily a textbook, the book also functions as a comprehensive reference to those in the industry.

Characterization of Impurities and Degradants Using Mass Spectrometry
Published June 2011
Both general practitioners in pharmaceutical research and specialists in analytical chemistry field will benefit from this book that will detail step-by-step approaches and new strategies to solve challenging problems related to pharmaceutical research.

Integrated Strategies for Drug Discovery Using Mass Spectrometry
Published June 2005
This book provides a thorough and unique review of current analytical approaches, industry practices, and strategies in drug discovery.

LC/MS Applications in Drug Development
Published March 2002
This book is the first to describe LC/MS applications within the context of drug development: discovery, preclinical, clinical, and manufacturing.